Face-Off is the first multi-player mode to be featured in the Guitar Hero series. It made its first appearance in Guitar Hero. In Face-Off, players take turns playing sections of a song or occasionally playing at the same time in a call-and-response-style game. Both players can select their own difficulty level and will not fail the song if multiple notes are missed. The objective of Face-Off is to have a higher score than your opponent at the end of the song. Face-Off has appeared in every main iteration of the Guitar Hero series up until Guitar Hero: Warriors of Rock.

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